Episode 1.39 Online Free Fixed
dividing the number needed to treat (NNT) for the prevention of depressive episodes by the NNT for the prevention of manic episodes. Drugs with a PI superior to one have stronger anti-manic versus anti-depressant prophylactic properties, whereas those with PI inferior to one are more effective for preventing depressive episodes than the manic ones. Drugs with the PI of one may have a comparable anti-manic and anti-depressive potential. A few examples of pharmacological agents with calculated PI include 12.09 for risperidone, 1.39 for lithium, 1.14 for quetiapine, and 0.40 for lamotrigine. Similarly, PI for psychological interventions include 0.33-0.89 for cognitive-behavioral therapy and 0.73-0.78 for psychoeducation.
Episode 1.39 Online Free